Shingles is caused by the same virus that causes Chickenpox, and after you have had Chickenpox, Shingles can return at any time in the form of painful blisters. 1 in 3 people will develop Shingles at some point in their life, with the risk of complications climbing significantly after 60 years of age. Shingles vaccine is currently available for free only for people older than 70 years, which leaves the 50–69-year cohort unprotected unless they pay out of pocket. The available Shingles vaccine, Shingrix, is 90% effective at preventing Shingles, but it causes a high percentage of injection site pain, swelling, and redness.
This research study is being conducted to research a new investigational Shingles vaccine, to see if it will protect against Shingles as effectively as Shingrix, but without the high percentage of injection site pain, swelling, and redness.
The study would require you to come to the clinic 5 times over 5 months. Visits will range between 15 mins to 60 minutes each time you come in. Over the course of the study, we will check your medical history, draw blood, and inject the study vaccine. You will also need to download an app on your phone to record data for 7 days following the vaccinations.
You will be reimbursed for your time and involvement in the research study.
- Aged between 50 and 69 years
- Not had a history of Shingles
- Never had a vaccine against Shingles or Chickenpox
- Never had or currently diagnosed with autoimmune conditions